Excel

Yes, if you wanted to multiply A1 to B1 and the answer to appear in C1, your formula in C1 would read:
=A1*B1

If you wanted to to subtract cell B1 off cell A1 and the answer to appear in C1, your formula in C1 would read:
=A1-B1

Similarily your other basic functions would be:
=A1/B1 for dividing
=A1+B1 for adding

Hope that helps.